Luteinizing hormone (LH) is a hormone produced by the anterior pituitary gland. In females, an acute rise of LH called the LH surge triggers ovulation and development of the corpus luteum. In males, where LH had also been called interstitial cell-stimulating hormone (ICSH) it stimulates Leydig cell production of testosterone. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for the specificity of the interaction with the LH receptor. This beta subunit contains an amino acid sequence that exhibits large homologies with that of the beta subunit of hCG and both stimulate the same receptor.
Species
Human
Protein Type
Native
Grade & Purity
> 98% pure
Source
Human pituitary glands
Form & Buffer
Lyophilized from 50 mM ammonium bicarbonate. Reconstitute with solvent of choice.
Storage
Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
