Specifications
| Materials of Construction |
| Structural Components |
Polycarbonate |
| Filter Support |
Polypropylene |
| Seal Ring |
Fluoroelastomer |
| Vent Cap |
PVDF |
| Chemistry |
| Durapore® |
Hydrophilic PVDF |
| Milligard |
Mixed Cellulose Esters |
|
Borosilicate Glass Fiber
Mixed Cellulose Esters |
| Lifegard |
Borosilicate Glass Fiber |
|
Polypropylene |
| Filtration Area, cm² |
17.7 |
| Maximum Operating Pressure, bar (psid) |
5.5 (80) @ 25 °C |
| Bacterial Endotoxins |
Aqueous extraction contains ≤0.25 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test |
| Oxidizable Substances |
Will meet the USP Oxidizable Substances Test requirements after a water flush of ≥100 mL |
| Component Material Toxicity |
Component materials meet the criteria of the USP <88> Reactivity Test for Class VI Plastics. These products meet the requirements of the USP <88> Safety Test, utilizing a 0.9% sodium chloride extraction. |
| Sterilization |
| OptiScale with Durapore or Polygard-CN media |
3 autoclave cycles of 60 min @ 126 °C; not in-line steam sterilizable |
| OptiScale with Milligard, Polysep II or Lifegard media |
3 autoclave cycles of 60 min @ 121 °C; not in-line steam sterilizable |
| Indirect Food Additive |
All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182. |
Description
OptiScale capsules are a family of convenient, disposable filters ideal for media selection, process screening and scaling. These "drop-in" filter devices, with a variety of media options, create an effective platform for rapidly evaluating biopharmaceuticals. OptiScale offers speed-to-market strategies for efficiently developing compounds and biotherapeutics.
From benchtop to manufacturing, OptiScale capsules complement Millipore's extensive line of filters. They offer the same selection of media types as Millipore's process scale filters.
Typical Applications
OptiScale capsules are ideal for evaluating media to clarify biological feed streams such as cell cultures, serum, plasma and vaccines containing high levels of colloidal particles.
The capsules are also effective prefilters for fine chemicals and purified water processing.
Benefits
- Scalable performance for speed-to-market
- Innovative design offers convenience and efficiency
- Faster than the 47 mm disc method
- Disposable, reliable, easy-to-use
- Choice of media optimizes your process development
- Peel and stick label for easy tracking
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